- 1 Schoen-Jackson Co.
- 1 Schoettle, F. Paper Box Factory
- 1 Schofield Mills
- 1 Schofield, Joseph Cotton & Woolen Waste
- 5 Scholars
- 1 Scholastica, Saint, 6th cent.
- 1 Schollenberger, W. & Sons Leather Manufactory
- 1 Schomacker Piano Co.
- 5 School children
- 18 School House Lane
- 2 School of Design
- 1 School of Industry
- 11 Schoolhouses
- 637 Schools
- 5 Schools (institutions)
- 9 Schooners
- 1 Schrack Paint Co.
- 1 Schroeder's Marble Yard
- 2 Schulkill Hose Company
- 1 Schull, D.J.-Coach Manufacturer
- 1 Schulz, Theodor, 1770-1850
- 1 Schumacher & Ettinger
- 1 Schumann's Tannery
- 1 Schutz, Anton Joseph Friedrich, 1894-1977
- 11 Schuykill Avenue
- 4 Schuylkill Arsenal
- 3 Schuylkill Fishing Company
- 1 Schuylkill Mills
- 226 Schuylkill River
- 112 Schwarzmann, H. J. (Hermann J.)
- 1 Schwarzwaelder Co. (rubberizing textile goods)
- 1 Schweigart Bros. American Dye Works
- 2 Schweitzer, Albert, 1875-1965
- 1 Schwenckfeld, Caspar, 1489-1561
- 10 Schwenkfelders
- 9 Science
- 16 Science museums (buildings)
- 2 Scientific equipment
- 20 Scientific illustrations (images)
- 2 Scientific illustrators
